DUBs-IN-3 |
| カタログ番号GC10356 |
DUBs-IN-3 は、参照化合物 22c から抽出された強力な脱ユビキチナーゼ (USP) 酵素阻害剤であり、USP8 の IC50 は 0.56 μM です。
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Cas No.: 924296-17-3
Sample solution is provided at 25 µL, 10mM.
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DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.
References:
[1]. Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.
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