Carboxypeptidase
A carboxypeptidase (CP) is an enzyme involved in the catabolism of proteins that cleaves amino acids from the C-terminal of proteins or large peptides through rapid hydrolysis at the last stages of protein cleavage. So far thirteen mammalian CPs encoded by thirteen known members of the metallocarboxypeptidase gene family and one human-specific CP (CPA3) have been identified. Based primarily on amino acid sequence similarities, metallocarboxypeptidases are divided into two subfamilies, including CPA/B family (CPA1, CPA2, CPB, MK-CPA and KPU) and CPN/E family (CPE/H, CPM, CPN, CPD, CPZ, CPX1, CPX2 and AEBP1). All members in CPA/B family are approximately 34-36 kDa proteins of optimal pH=7; while all members in CPN/E family range in size and pH optima.
Products for Carboxypeptidase
- Cat.No. Product Name Information
- GC60471 2-Benzylsuccinic acid 2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an potent inhibitor of carboxypeptidase A (CPA).
- GC11804 2-Guanidinoethylmercaptosuccinic Acid 2-Guanidinoethylmercaptosuccinic Acid (2-Guanidinoethylmercaptosuccinic acid) is a potent specific inhibitor of carboxypeptidase B-like processing enzyme (encephalin convertase) with the Ki value of 8.8 nM.
- GC17937 2-MPPA glutamate carboxypeptidase II (GCP II) inhibitor
- GC35608 Carboxypeptidase G2 (CPG2) Inhibitor Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
- GC35741 CPA inhibitor CPA inhibitor (Carboxypeptidase inhibitor; compound 5) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.
- GC63338 GCPII-IN-1 TFA GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM.
- GC13467 PMPA (NAALADase inhibitor) A potent inhibitor of GCP II/NAALADase
- GC18065 ZJ 43