Other Signal Transduction

Signal Transduction
Cellular responses are triggered by proteins, drugs, or pathogens binding to specific receptors. Receptor mediated signaling is a cascade of enzymatic reactions that amplifies the signal. The agonists and antagonists modulating receptor functionality are essential tools for research and medical practice. read more
Targets for Other Signal Transduction
Products for Other Signal Transduction
- Cat.No. Product Name Information
-
GC49890
β-Glycerophosphate-d5 (sodium salt hydrate)
Glycerol 2-Phosphate-d5
An internal standard for the quantification of β-glycerophosphate -
GC45304
1,3-Dipalmitoyl-rac-glycerol
DG(16:0/0:0/16:0), 1,3-Dipalmitin
-
GC13863
10Panx
10Panx
A peptide inhibitor of PANX1 -
GC49912
13C20,15N10-Cyclic di-GMP (sodium salt)
13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguanylate, 13C20,15N10-3’,5’-Cyclic diguanylic Acid
An internal standard for the quantification of cyclic di-GMP -
GC52141
2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide
-
GC52129
3-Amino-5-hydroxybenzoic Acid
AHBA
-
GC49494
4-Aminobenzylphosphonic Acid
4-ABPA, NSC 12117
An alkaline phosphatase inhibitor -
GP10121
Ac-Endothelin-1 (16-21), human
Ac-His-Leu-Asp-Ile-Ile-Trp-OH
-
GP10059
Acetyl Angiotensinogen (1-14), porcine
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH
-
GC50003
AG 490
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
-
GP10076
Agouti-related Protein (AGRP) (25-82), human
H2N-Leu-Ala-Pro-Met-Glu-Gly-Ile-Arg-Arg-Pro-Asp-Gln-Ala-Leu-Leu-Pro-Glu-Leu-Pro-Gly-Leu-Gly-Leu-Arg-Ala-Pro-Leu-Lys-Lys-Thr-Thr-Ala-Glu-Gln-Ala-Glu-Glu-Asp-Leu-Leu-Gln-Glu-Ala-Gln-Ala-Leu-Ala-Glu-Val-Leu-Asp-Leu-Gln-Asp-Arg-Glu-Pro-Arg-OH
-
GC49110
AICA Ribonucleotide
AICA-Ribotide, AICA-Riboside-5'-phosphate, 5-Aminoimidazole-4-Carboxamide Ribonucelotide, NSC 283955, NSC 292227
An AMPK activator -
GC52361
AMARA Peptide (trifluoroacetate salt)
AMARAASAAALARRR-OH, H-Ala-Met-Ala-Arg-Ala-Ala-Ser-Ala-Ala-Ala-Leu-Ala-Arg-Arg-Arg-OH
A peptide substrate for AMPK -
GC91790
AMG PERK 44 (hydrochloride)
AMG PERK 44 is a protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 6 nM).
-
GP10077
Angiotensin (1-7)
Asp-Arg-Val-Tyr-Ile-His-Pro
Ang-(1-7) (H - Asp - Arg - Val - Tyr - Ile - His - Pro - OH) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively[1].
-
GP10074
Angiotensin 1/2 (1-5)
H2N-Asp-Arg-Val-Tyr-Ile-OH
-
GP10067
Angiotensin 1/2 (1-6)
H2N-Asp-Arg-Val-Tyr-Ile-His-OH
-
GP10144
Angiotensin 1/2 (1-7) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide
-
GP10012
Angiotensin 1/2 (1-8) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide
Vasoconstrictor
-
GP10025
Angiotensin 1/2 (1-9)
-
GP10045
Angiotensin 1/2 (2-7)
H2N-Arg-Val-Tyr-Ile-His-Pro-OH
Vasoconstrictor
-
GP10079
Angiotensin 1/2 (5-7)
H2N-Ile-His-Pro-OH
-
GP10120
Angiotensin 1/2 + A (2 - 8)
H2N-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Vasoconstrictor -
GP10087
Angiotensin I (human, mouse, rat)
-
GP10023
Angiotensin II
Angiotensin II is a vasoconstrictor and the main bioactive peptide of the renin/Angiotensin system.
-
GP10110
Angiotensin III (human, mouse)
An agonist at AT1 and AT2 receptors
-
GP10137
ANP (1-11), rat
H2N-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH
-
GC91040
AP-1
A PROTAC that drives ALK degradation
-
GP10061
Atrial Natriuretic Factor (1-29), chicken
H2N-Met-Met-Arg-Asp-Ser-Gly-Cys-Phe-Gly-Arg-Arg-Ile-Asp-Arg-Ile-Gly-Ser-Leu-Ser-Gly-Met-Gly-Cys-Asn-Gly-Ser-Arg-Lys-Asn-OH
Atrial Natriuretic Factor (1-29), chicken, (C130H223N51O41S5), a peptide with the sequence H2N-SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-OH, MW= 3316.8. -
GC91849
Autocamtide-2-related Inhibitory Peptide (trifluoroacetate salt)
Autocamtide-2-related inhibitory peptide is a calmodulin-dependent protein kinase II (CaMKII) inhibitor (IC50 = 40 nM) that was designed based on the sequence around the autophosphorylation site (Thr286/Thr287) in the autoinhibitory domain of the protein kinase.
-
GC49403
Benzarone
L 2197, NSC 82134
An active metabolite of benzbromarone -
GC49300
BIM-46187 (hydrochloride)
An inhibitor of heterotrimeric G-protein signaling
-
GC19508
BLU-782
Activin Receptor-like Kinase 2 Inhibitor 1, ALK2-IN-1, Fidrisertib
BLU-782 is an oral precision therapy specifically designed to selectively target mutant ALK2. -
GC91140
BMS 502
An inhibitor of DGK-α, DGK-ζ, and DGK-ι
-
GP10071
BNP (1-32), human
-
GC49079
C82
An Mtb CdnP inhibitor
-
GC49332
Calcineurin Substrate (trifluoroacetate salt)
H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH, H-DLDVPIPGRFDRRVSVAAE-OH
A synthetic peptide substrate -
GC49433
Capsiate
A capsaicin analog with diverse biological activities
-
GC48992
CGP 77675 (hydrate)
An inhibitor of Src family kinases
-
GC49392
CHIR98024
CT 98024
A GSK3 inhibitor -
GC49334
Chroman 1 (hydrochloride hydrate)
(S)-Chroman 1
A ROCK2 inhibitor -
GC49556
Cl-Necrostatin-1
7-Cl-Nec-1, 7-Cl-Necrostatin-1, Nec-1f
A RIPK1 inhibitor -
GP10134
coagulation factor II (thrombin) B chain fragment [Homo sapiens]
H2N-Lys-Pro-Val-Ala-Phe-Ser-Asp-Tyr-Ile-His-Pro-Val-Cys-Leu-Pro-Asp-Arg-OH
-
GP10010
COG 133
Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu
-
GC43304
Compound 43 TAO Kinase Inhibitor
Compound 43 TAO kinase inhibitor is an ATP-competitive inhibitor of the thousand-and-one amino acid kinases TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively).
-
GC43326
CRT0066101 (hydrochloride)
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling.
-
GC43506
D-myo-Inositol-1,2,3,5,6-pentaphosphate (sodium salt)
Ins(1,2,3,5,6)-P5, 1,2,3,5,6-IP5
D-myo-inositol-1,2,3,5,6-pentaphosphate (Ins(1,2,3,5,6)-P5) (sodium salt) is produced from Ins(1,2,3,4,5,6)P6 via a minor enzymatic phytate degradation pathway by K. -
GC43507
D-myo-Inositol-1,2,3,5-tetraphosphate (sodium salt)
Ins(1,2,3,5)P4 (sodium salt), 1,2,3,5IP4 (sodium salt)
D-myo-Inositol-1,2,3,5-tetraphosphate (Ins(1,2,3,5)P4) is one of the many inositol phosphate isomers that could act as small, soluble second messengers in the transmission of cellular signals. -
GC43509
D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt)
Ins(1,2,4,5,6)P5 (sodium salt), 1,2,4,5,6IP5 (sodium salt)
D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt) (Ins(1,2,4,5,6)P5 (sodium salt)) is one of several different inositol oligophosphate isomers implicated in signal transduction. -
GC43510
D-myo-Inositol-1,2,4,5-tetraphosphate (sodium salt)
Ins(1,2,4,5)P4, 1,2,4,5IP4
Ins(1,2,4,5)P4 is one of the many inositol phosphate (InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals.. -
GC43512
D-myo-Inositol-1,2,6-triphosphate (sodium salt)
Ins(1,2,6)P3, 1,2,6IP3
D-myo-Inositol-1,2,6-phosphate (Ins(1,2,6)-P3) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. -
GC43515
D-myo-Inositol-1,3,4,5,6-pentaphosphate (sodium salt)
Ins(1,3,4,5,6)P5, 1,3,4,5,6IP5
The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents. -
GC43518
D-myo-Inositol-1,3,4-triphosphate (sodium salt)
Ins(1,3,4)P3 (sodium salt), 1,3,4IP3 (sodium salt)
The inositol phosphates play a critical role as small, soluble second messengers in transmission of cellular signals. -
GC43519
D-myo-Inositol-1,3,5-triphosphate (sodium salt)
Ins(1,3,5)P3 (sodium salt), 1,3,5IP3 (sodium salt)
D-myo-Inositol-1,3,5-phosphate (Ins(1,3,5)P3) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. -
GC43525
D-myo-Inositol-1,4-diphosphate (sodium salt)
Ins(1,4)P2 (sodium salt), 1,4IP2 (sodium salt)
D-myo-Inositol-1,4-phosphate (Ins(1,4)P2) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. -
GC43527
D-myo-Inositol-1,5-diphosphate (sodium salt)
Ins(1,5)P2, 1,5IP2
D-myo-Inositol-1,5-phosphate (Ins(1,5)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. -
GC43528
D-myo-Inositol-1-phosphate (cyclohexyl ammonium salt)
Ins(1)P1 (cyclohexyl ammonium salt), 1IP1 (cyclohexyl ammonium salt)
D-myo-Inositol-1-phosphate (Ins(1)P1) is a member of the inositol phosphate molecular family of second messengers that play critical roles in intracellular signaling. -
GC43529
D-myo-Inositol-1-phosphate (sodium salt)
Ins(1)P1 (sodium salt), 1IP1 (sodium salt)
D-myo-Inositol-1-phosphate (Ins(1)P1) is a member of the inositol phosphate (InsP) molecular family of second messengers that play a critical role in the transmission of cellular signals. -
GC43531
D-myo-Inositol-2,3,5,6-tetraphosphate (sodium salt)
2,3,5,6IP4 (sodium salt), Ins(2,3,5,6)P4 (sodium salt)
D-myo-inositol-2,3,5,6-tetraphosphate (sodium salt) (Ins(2,3,5,6)-P4 (sodium salt)) is produced from Ins(1,2,3,5,6)P5 via a minor enzymatic phytate degradation pathway by K. -
GC43534
D-myo-Inositol-2,4-diphosphate (sodium salt)
Ins(2,4)P2 (sodium salt), 2,4IP2 (sodium salt)
The inositol phosphates are a family of mono- to poly-phosphorylated compounds that act as messengers, regulating cellular functions including cell cycling, apoptosis, differentiation, and motility. -
GC43535
D-myo-Inositol-2,5,6-triphosphate (sodium salt)
Ins(2,5,6)P3 (sodium salt), 2,5,6IP3 (sodium salt)
Ins(2,5,6)P3 (sodium salt) is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. -
GC43537
D-myo-Inositol-3,4,5-triphosphate (sodium salt)
Ins(3,4,5)P3, 3,4,5IP4
D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)-P3) is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. -
GC43538
D-myo-Inositol-3-phosphate (sodium salt)
Ins(3)P1 (sodium salt), 3IP1 (sodium salt)
D-myo-Inositol-3-phosphate (Ins(3)P1) is a member of the inositol phosphate (InsP) molecular family of second messengers that play a critical role in the transmission of cellular signals. -
GC43539
D-myo-Inositol-4,5-diphosphate (sodium salt)
Ins(4,5)P2 (sodium salt), 4,5IP2 (sodium salt)
D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a key second messenger produced in cells by PLC-mediated hydrolysis of phosphatidylinositol-4,5-diphosphate. -
GC45894
Daunorubicin-13C-d3
A neuropeptide with diverse biological activities
-
GC41151
Decursinol angelate
Decursinol angelate is a pyranocoumarin that has been found in the Korean medicinal herb A.
-
GC49789
Dihydronarwedine
(–)-Dihydrogalanthaminone, (–)-Lycoraminone
An alkaloid and GSK3β inhibitor -
GP10022
Dynamin inhibitory peptide
Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro
-
GC13855
Eeyarestatin I
Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. It disturbs endoplasmic reticulum (ER) homeostasis and has anticancer activities resembling that of Bortezomib. Eeyarestatin I inhibits Sec61 translocon.
-
GP10030
EGF receptor substrate eps15 acetyl - [Mus musculus]/[Homo sapiens]
Ac-Gln-Glu-Gln-Glu-Asp-Leu-Glu-Leu-Ala-Ile-Ala-Leu-Ser-Lys-Ser-Glu-Ile-Ser-Glu-Ala-OH
EGF receptor substrate eps15 (Eps15) has been identified as a 142-kDa substrate of the EGF receptor1. -
GP10108
EGF-R (661-681) T669 Peptide
H2N-Lys-Arg-Glu-Leu-Val-Glu-Pro-Leu-Thr-Pro-Ser-Gly-Glu-Ala-Pro-Asn-Gln-Ala-Leu-Leu-Arg-OH
-
GC52002
Emavusertib
CA-4948
-
GP10065
Endomorphin-1
-
GP10117
Endostatin (84-114)-NH2 (JKC367)
H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2
-
GP10062
Endothelin-1 (1-15), amide, human
H2N-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-NH2
-
GC52336
ENPP1 Inhibitor 43
An ENPP1 inhibitor
-
GC52277
ENPP3 Inhibitor
An ENPP3 inhibitor
-
GC52362
ENPP3 Inhibitor 4g
An ENPP1 and ENPP3 inhibitor
-
GC52322
ENPP3 Inhibitor 4t
An ENPP3 inhibitor
-
GP10005
Epidermal growth factor receptor (994-1002) acetyl/amide
Ac-Asp-Ser-Asn-Phe-Tyr-Arg-Ala-Leu-Met-amide
EGF-family receptor
-
GP10095
Epidermal Growth Factor Receptor Peptide (985-996)
H2N-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH
-
GP10132
erbB-2
H2N-Lys-Ile-Phe-Gly-Ser-Leu-Ala-Phe-Leu-OH
-
GC49074
Forphenicine
A bacterial metabolite and an inhibitor of alkaline phosphatase
-
GP10092
G protein coupled receptor [Homo sapiens]
H2N-Gln-Glu-Ser-His-Asn-Ser-Gly-Asn-Arg-Ser-Asp-Gly-Pro-Gly-Lys-Asn-Thr-Thr-Leu-His-Asn-Glu-Phe-Asp-Thr-OH
G protein coupled receptor [Homo sapiens], (C110H168N38O45), a peptide with the sequence H2N-QESHNSGNRSDGPGKNTTLHNEFDT-OH, MW= 2742.74. -
GP10107
Gap 26
Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg
Gap 26, as a connexin mimetic peptide, which has the SHVR amino acid regions contributing crucially to the docking of connexons to generate gap junctions. -
GP10119
Gap 27
Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile
A connexin-mimetic peptide
-
GC25450
GATA4-NKX2-5-IN-1
3i-1000
GATA4-NKX2-5-IN-1 (3i-1000) is a small-molecule compound inhibiting GATA4 and NKX2-5 transcriptional synergy with IC50 of 3 uM
-
GP10122
Glucagon (19-29), human
H2N-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
-
GP10024
Growth Hormone (1-43), human
H2N-Phe-Pro-Thr-Ile-Pro-Leu-Ser-Arg-Leu-Phe-Asp-Asn-Ala-Met-Leu-Arg-Ala-His-Arg-Leu-His-Gln-Leu-Ala-Phe-Asp-Thr-Tyr-Gln-Glu-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-OH
Human Growth Hormone (1-43) peptide -
GC49284
GSK-A1
A PI4KIIIα inhibitor
-
GP10004
GTP binding protein 1 fragment [Multiple species]
H2N-Lys-Val-Ile-Thr-Phe-Ile-Asp-Leu-OH
Signal transducing molecules -
GP10115
GTP-Binding Protein Fragment, G alpha
H2N-Cys-Gly-Ala-Gly-Glu-Ser-Gly-Lys-Ser-Thr-Ile-Val-Lys-Gln-Met-Lys-OH
-
GP10041
Insulin like growth factor II fragment variant
H2N-Thr-Pro-Thr-Lys-Ser-Glu-Arg-OH
Insulin like growth factor II fragment variant has a sequence of Thr-Pro-Thr-Lys-Ser-Glu-Arg. -
GP10029
Interleukin II (60-70)
H2N-Leu-Thr-Phe-Lys-Phe-Tyr-Met-Pro-Lys-Lys-Ala-OH
Cytokine,regulating WBC
-
GC52328
KYL (trifluoroacetate salt)
KYL Peptide
An EphA4 inhibitor -
GC17779
Levetiracetam
UCBL 059
Antiepileptic drug -
GC39256
LP-935509
LP-935509 is an orally active, potent, selective, ATP-competitive and brain-penetrant inhibitor of adaptor protein-2 associated kinase 1 (AAK1) with an IC50 of 3.3 nM and a Ki of 0.9 nM, respectively.
-
GC19775
M2N12
M2N12
-
GP10140
MAP kinase fragment [Multiple species]
H2N-Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu-OH
-
GP10066
Melanocyte stimulating hormone release inhibiting factor
Pro-Leu-Gly