2-Thio-UTP |
Catalog No.GB20143 |
Base modified ribonucleoside triphosphates. RNAs prepared from 2-Thio-UTP is less immunogenic as compared to unmodified RNA.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Base modified ribonucleoside triphosphates. RNAs prepared from 2-Thio-UTP is less immunogenic as compared to unmodified RNA. 2-Thio-U modified mRNA shows no activation of RNA-dependent protein kinase, significantly reduced levels of 2'-5'-oligoadenylate synthetase activation, reduced levels of retinoic acid-inducible protein I and suppression of activation of Toll-like receptors.
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