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γ-Glutamyl-S-allylcysteine

Catalog No.GC63681 Copy One-Click Copy Product Info

γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic.

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γ-Glutamyl-S-allylcysteine Chemical Structure

Cas No.: 91216-95-4

Size Price Stock Qty
10mM (in 1mL Water)
$257.00
In stock
5mg
$234.00
In stock
10mg
$351.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of γ-Glutamyl-S-allylcysteine

γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities[1][2].

γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine; 0.1-2.5 mg/mL) inhibits the increase of fluorescence intensity at about 440 nm in a concentration-dependent manner and reduces reacted free lysine side chains[1]. γ-Glutamyl-S-allylcysteine (2.5 mg/mL) prevents Glycation-specific decline in BSA α-helix content and increase in β-sheet in vitro[1]. γ-Glutamyl-S-allylcysteine (2.5 mg/mL) suppresses protein crosslinking to form polymers[1]. γ-Glutamyl-S-allylcysteine (10, 40, 160 μg/mL) shows radical-scavenging and metal-chelating capacities[1].

[1]. Dehong Tan, et al. Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativum L.). Nat Prod Res. 2015;29(23):2219-22.
[2]. Yi-Yu Chen, et al. Enzymatic synthesis of γ-L-glutamyl-S-allyl-L-cysteine, a naturally occurring organosulfur compound from garlic, by Bacillus licheniformis γ-glutamyltranspeptidase. Enzyme Microb Technol. Jul-Aug 2015;75-76:18-24.

Chemical Properties of γ-Glutamyl-S-allylcysteine

Cas No. 91216-95-4 SDF
Formula C11H18N2O5S M.Wt 290.34
Solubility Water : 33.33 mg/mL (114.80 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of γ-Glutamyl-S-allylcysteine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.4442 mL 17.2212 mL 34.4424 mL
5 mM 688.8 μL 3.4442 mL 6.8885 mL
10 mM 344.4 μL 1.7221 mL 3.4442 mL
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In vivo Formulation Calculator (Clear solution) of γ-Glutamyl-S-allylcysteine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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