Alamethicin F50 (Synonyms: 18-L-Glutamine Alamethicin I) |
| Catalog No.GC42763 |
Alamethicin F50 is a peptaibol isolated from Trichoderma.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 56165-93-6
Sample solution is provided at 25 µL, 10mM.
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Alamethicin F50 is a peptaibol isolated from Trichoderma. It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids. Alamethicin F50 is a mixture of 13 different peptides, with the most abundant designated as alamethicin F50/5. Alamethicin F50 forms voltage-dependent ion channels in lipid membranes and acts as a lytic agent. It induces lysis of leukocytes (IC50 = 54 and 80 μM for rat mast cells and mouse spleen lymphocytes, respectively) and exhibits antibacterial activity against a panel of 8 mollicutes (MICs = 1.56-12.5 μM).
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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