Caloxin 2A1 (trifluoroacetate salt) (Synonyms: VSNSNWPSFPSSGGG-NH2) |
| Catalog No.GC47021 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Caloxin 2A1 is a peptide plasma membrane Ca2+/Mg2+-ATPase inhibitor (IC50 = 0.4 mM in erythrocyte leaky ghosts).1 It is selective for the plasma membrane Ca2+/Mg2+-ATPase over the erythrocyte ghost Mg2+- and Na+/K+-ATPases and the skeletal muscle sarcoplasmic reticulum Ca2+/Mg2+-ATPase at 0.9 mM. Caloxin 2A1 (0.34 mM) induces relaxation in precontracted rat aortic rings, an effect that can be reversed by the nitric oxide synthase inhibitor L-NAME .
1.Chaudhary, J., Walia, M., Matharu, J., et al.Caloxin: A novel plasma membrane Ca2+ pump inhibitorAm. J. Physiol. Cell Physiol.280(4)C1027-C1030(2001)
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