CATPB |
| Catalog No.GC50293 |
FFA2 (GPR43) inverse agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1322598-09-3
Sample solution is provided at 25 µL, 10mM.
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FFA2 inverse agonist (pKi = 7.87). Selective for human over mouse FFA2. Increases forskolin-induced cAMP production and inhibits acetate-induced MAPK signaling in cells expressing human FFA2.
Park et al (2016) Selective novel inverse agonists for human GPR43 augment GLP-1 secretion. Eur.J.Pharmacol. 771 1 PMID:26683635 |Sergeev et al (2016) Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands. J.Biol.Chem. 291 303 PMID:26518871
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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