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Cefepime Dihydrochloride Monohydrate

Catalog No.GC13111

Cefepime Dihydrochloride Monohydrate Chemical Structure

broad-spectrum cephalosporin

Size Price Stock Qty
500mg
$36.00
In stock
1g
$68.00
In stock
5g
$158.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria[1].

Cefepime is an extended-spectrum parenteral cephalosporin antibiotic active in vitro against a broad spectrum of gram-positive and gram-negative aerobic bacteria. Cefepime has a decreased propensity to induce beta-lactamases compared with other beta-lactam antibiotics[1].

Cefepime has a pharmacokinetic disposition similar to that of other renally eliminated cephalosporins, with a half-life of approximately 2 hours. Cefepime has demonstrated clinical efficacy against a variety of infections, including urinary tract infections, pneumonia, and skin and skin structure infections. Cefepime is generally well tolerated[2].

References:
[1]. Neu, H.C., Safety of cefepime: a new extended-spectrum parenteral cephalosporin. Am J Med, 1996. 100(6A): p. 68S-75S.
[2]. Wynd, M.A. and J.A. Paladino, Cefepime: a fourth-generation parenteral cephalosporin. Ann Pharmacother, 1996. 30(12): p. 1414-24.

Chemical Properties

Cas No. 123171-59-5 SDF
Chemical Name (1S,8R)-8-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-4-((1-methylpyrrolidin-1-ium-1-yl)methyl)-7-oxo-2-thiabicyclo[4.2.0]oct-4-ene-5-carboxylate dihydrochloride hydrate
Canonical SMILES NC1=NC(/C(C(N[C@H]2[C@]3([H])C(C(C([O-])=O)=C(C[N+]4(C)CCCC4)CS3)C2=O)=O)=N/OC)=CS1.Cl.Cl.O
Formula C20H29Cl2N5O6S2 M.Wt 570.5
Solubility ≥ 57.1mg/mL in DMSO Storage 4°C, away from moisture and light
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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