Chlorpyrifos-d10 |
| Catalog No.GC47083 |
An internal standard for the quantification of chlorpyrifos
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 285138-81-0
Sample solution is provided at 25 µL, 10mM.
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Chlorpyrifos-d10 is intended for use as internal standard for the quantification of chlorpyrifos by GC- or LC-MS. Chlorpyrifos is an organophosphate insecticide.1,2 It is lethal to A. melinus, G. ashmeadi, E. eremicus, and E. formosa adults (LC50s = 0.8, 6, 12, and 17 ng/ml, respectively).1 Chlorpyrifos induces mortality in O. insidiosus adults when applied to corn, sorghum, and alfalfa plants.2 It is toxic to mice (LD50 = 155 mg/kg).3 Postnatal day 11 to 14 exposure to chlorpyrifos (3 mg/kg) decreases nest building and defense behaviors in adult female mice.4 Formulations containing chlorpyrifos have been used in the control of insects in agriculture.
1.Prabhaker, N., Morse, J.G., Castle, S.J., et al.Toxicity of seven foliar insecticides to four insect parasitoids attacking citrus and cotton pestsJ. Econ. Entomol.100(4)1053-1061(2007) 2.Al-Deeb, M.A., Wilde, G.E., and Zhu, K.Y.Effect of insecticides used in corn, sorghum, and alfalfa on the predator Orius insidiosus (Hemiptera: Anthocoridae)J. Econ. Entomol.94(6)1353-1360(2001) 3.Guo, J.-X., Wu, J.J.-Q., Wight, J.B., et al.Mechanistic insight into acetylcholinesterase inhibition and acute toxicity of organophosphorus compounds: A molecular modeling studyChem. Res. Toxicol.19(2)209-216(2006) 4.Venerosi, A., Cutuli, D., Colonnello, V., et al.Neonatal exposure to chlorpyrifos affects maternal responses and maternal aggression of female mice in adulthoodNeurotoxicol. Teratol.30(6)468-474(2008)
| Cas No. | 285138-81-0 | SDF | |
| Canonical SMILES | ClC1=NC(OP(OC([2H])([2H])C([2H])([2H])[2H])(OC([2H])([2H])C([2H])([2H])[2H])=S)=C(Cl)C=C1Cl | ||
| Formula | C9HCl3D10NO3PS | M.Wt | 360.6 |
| Solubility | H2O : 100 mg/mL (277.28 mM; Need ultrasonic); DMSO : 50 mg/mL (138.64 mM; Need ultrasonic) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.7732 mL | 13.8658 mL | 27.7316 mL |
| 5 mM | 0.5546 mL | 2.7732 mL | 5.5463 mL |
| 10 mM | 0.2773 mL | 1.3866 mL | 2.7732 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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