Cystinyl-bis-glycine (Synonyms: (Cys-Gly)2, (H-Cys-Gly-OH)2, NSC 333711) |
| Catalog No.GC47161 |
A dipeptide intermediate in GSSG synthesis
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Cas No.: 7729-20-6
Sample solution is provided at 25 µL, 10mM.
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Cystinyl-bis-glycine is a dipeptide intermediate in the synthesis of oxidized glutathione that is composed of two cysteinylglycine peptides linked by a disulfide bond.1 It is formed via nonenzymatic oxidation of cysteinylglycine, a glutathione catabolite produced by γ-glutamyl transpeptidase.1,2
1.Griffith, O.W., and Tate, S.S.The apparent glutathione oxidase activity of γ-glutamyl transpeptidase. Chemical mechanismJ. Biol. Chem.255(11)5011-5014(1980) 2.Kozak, E.M., and Tate, S.S.Glutathione-degrading enzymes of microvillus membranesJ. Biol. Chem.257(11)6322-6327(1982)
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