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Danofloxacin-d3-1

Catalog No.GC72524 Copy One-Click Copy Product Info

Danofloxacin-d3-1 is deuterium labeled Danofloxacin.

Products are for research use only. Not for human use. We do not sell to patients.

Danofloxacin-d3-1 Chemical Structure

Cas No.: 1217683-55-0

Size Price Stock Qty
5 mg
$135.00
In stock
10 mg
$207.00
In stock

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Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Danofloxacin-d3-1

Danofloxacin-d3-1 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase.

References:
[1]. Erjie Tian, et al. Population Pharmacokinetics for Danofloxacin in the Intestinal Contents of Healthy and Infected Chickens. J Vet Pharmacol Ther. 2019 Sep;42(5):556-563.
[2]. Xia Xiao, et al. Comparative Pharmacokinetics of Danofloxacin in Healthy and Pasteurella Multocida Infected Ducks. J Vet Pharmacol Ther. 2018 Dec;41(6):912-918.

Chemical Properties of Danofloxacin-d3-1

Cas No. 1217683-55-0 SDF
Formula C19H17D3FN3O3 M.Wt 360.4
Solubility Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Danofloxacin-d3-1

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.7747 mL 13.8735 mL 27.7469 mL
5 mM 554.9 μL 2.7747 mL 5.5494 mL
10 mM 277.5 μL 1.3873 mL 2.7747 mL
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In vivo Formulation Calculator (Clear solution) of Danofloxacin-d3-1

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for Danofloxacin-d3-1

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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