Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Produkte für Metabolism
- Bestell-Nr. Artikelname Informationen
- GC46387 1,3,7-Trimethyluric Acid-d9 An internal standard for the quantification of 1,3,7-trimethyluric acid
- GC41846 1,3-Dioctanoyl-2-Oleoyl-rac-glycerol 1,3-Dioctanoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position.
- GC41849 1,3-Dipalmitoleoyl-rac-glycerol 1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions.
- GC40167 1,3-Dipalmitoyl-2-Docosahexaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-docosahexaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position.
- GC41850 1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-eicosapentaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position.
- GC19528 1,4-Benzoquinone A toxic metabolite of benzene
-
GC41858
1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)
1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis.
- GC40741 1,6-Anhydro-D-galactose 1,6-Anhydro-D-galactose is a carbohydrate found in liquid smoke flavorings that is used as a tracer of the contribution of biomass burning to total atmospheric particulate matter.
- GC40328 1,7-Dimethyluric Acid 1,7-DimethylurinsÄure ist der Metabolit von Koffein.
- GC42051 1-β-D-Glucosylsphingosine (d18:1) 1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides.
- GC49294 1-(4-Chlorobenzhydryl)piperazine An inactive metabolite of meclizine and chlorcyclizine
- GC46477 1-Amino-1-deoxy-D-fructose (hydrochloride) An amino monosaccharide
- GC39221 1-Cyclohexyl-3-dodecyl urea 1-Cyclohexyl-3-dodecylharnstoff (CDU; N-Cyclohexyl-N-dodecylharnstoff; NCND) ist ein hochselektiver Hemmer der lÖslichen Epoxidhydrolase (sEH).
- GC17913 1-Deazaadenosine 1-Deazaadenosin ist ein potenter Adenosin-Deaminase (ADA)-Hemmer mit einem Ki-Wert von 0,66 μM. 1-Deazaadenosin zeigt in vitro AntikrebsaktivitÄten und hat das Potenzial, ein Chemotherapeutikum fÜr lymphoproliferative Erkrankungen zu sein.
- GC10430 1-Deoxygalactonojirimycin (hydrochloride) 1-Desoxygalactonojirimycin (Hydrochlorid) (GR181413A) ist ein potenter und kompetitiver Inhibitor von α-Galactosidase A (⋱-Gal A) mit einem IC50 von 0,04
- GC18609 1-Deoxysphinganine (m18:0) 1-Desoxysphinganin (m18:0) (ES-285) ist eine antiproliferative (antitumorale) Verbindung marinen Ursprungs. 1-Desoxysphinganin (m18:0) hemmt das Wachstum der PC-3- und LNCaP-Zellen der Prostata durch intrazellulÄre Ceramid-Akkumulation und PKCζ Aktivierung.
- GC33073 1-Ethynylnaphthalene 1-Ethynylnaphthalin ist ein selektiver Inhibitor von Cytochrom P450 1B1.
- GC35065 1-Linoleoyl Glycerol 1-Linoleoylglycerin ist ein FettsÄureglycerin.
- GC35068 1-Monomyristin 1-Monomyristin, extrahiert aus Serenoa repens, hemmt die Hydrolyse von 2-Oleoylglycerol (IC50=32 μM) und die AktivitÄt der FettsÄureamidhydrolase (FAAH) (IC50=18 μM).
- GC33457 1-Naphthaleneacetic acid (1-Naphthylacetic acid) 1-NaphthylessigsÄure (1-NaphthylessigsÄure) (1-NaphthylessigsÄure), ein synthetisches Auxin, kann das Pflanzenwachstum fÖrdern.
- GC13379 1-Naphthyl 3,5-dinitrobenzoate dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor
- GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.
- GC42029 1-Palmitoyl-2-linoleoyl PE Phosphatidylethanolamines are important components of cell membranes and biochemical pathways of fatty acid synthesis.
- GC49366 1-Salicylate Glucuronide A metabolite of salicylic acid and aspirin
- GC42039 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC42040 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE
- GC42041 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC42042 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC42049 1-thio-β-D-Glucose (sodium salt) 1-thio-β-D-Glucose is an analog of β-D-glucose in which sulfur replaces the hydroxyl group at the one position.
- GC48782 10,13-epoxy-11-methyl-Octadecadienoic Acid A furan fatty acid
- GC49872 10-Formyltetrahydrofolate (sodium salt) (technical grade) 10-Formyltetrahydrofolat (Natriumsalz) (technische QualitÄt) ist eine Form von TetrahydrofolsÄure, die als Spender von Formylgruppen im Anabolismus wirkt.
- GC49118 10-hydroxy Warfarin A metabolite of (R)-warfarin
- GC41867 10-Nitrolinoleate 10-Nitrolinoleat ist ein potenter Peroxisom-Proliferator-aktivierter Rezeptor γ (PPARγ) Agonist.
- GC41868 10-Nitrooleate 10-Nitrooleat (CXA-10), eine NitrofettsÄure, hat potenzielle Wirkungen bei KrankheitszustÄnden, bei denen oxidativer Stress, EntzÜndungen, Fibrose und/oder direkte GewebetoxizitÄt eine bedeutende Rolle spielen.
- GC52026 10-oxo-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite
- GC52071 10-oxo-12(Z)-Octadecenoic Acid A metabolite of linoleic acid and an activator of TRPV1
- GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid
- GC40319 10-PAHSA 10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC11055 10-Pyrene-PC A substrate for some PLA2s
- GC41410 11β-Prostaglandin E2 11β-Prostaglandin E2 (11β-Dinoproston), ein Prostanoid-Derivat, hemmt die [3H]PGE2-Bindung an Hypothalamusmembranen bei der Ratte mit einem Ki von 53,3 nM.
- GC10821 11-keto-β-Boswellic Acid 11-Keto-beta-BoswelliasÄure (11-Keto-β-BoswelliasÄure) ist eine pentazyklische TriterpensÄure des Oleogumharzes aus der Rinde des Boswellia-Serratbaums, im Volksmund bekannt als Indischer Weihrauch. Die entzÜndungshemmende Wirkung von 11-Keto-beta-BoswelliasÄure beruht hauptsÄchlich auf der Hemmung der 5-Lipoxygenase (5-LOX) und der anschließenden Leukotrien- und Kernfaktor-Kappa-B-Aktivierung (NF-&7#954;B) und der Bildung des Tumor-Nekrose-Faktors Alpha Produktion.
- GC63796 116-9e 116-9e (MAL2-11B) ist ein Hsp70-Co-Chaperon-DNAJA1-Inhibitor.
- GC64008 12-O-Methylcarnosic acid 12-O-MethylcarnosinsÄure (12-MethoxycarnosinsÄure), eine aus dem Acetonextrakt von Salvia microphylla isolierte DiterpencarnosinsÄure, ist ein aktiver Bestandteil der 5α-Reduktase-Hemmung mit einem IC50-Wert von 61,7 μM.
-
GC41434
13,14-dihydro Prostaglandin F2α
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.
- GC41436 13,14-dihydro-15-keto Prostaglandin F1α 13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach.
- GC46435 13-cis-Retinoic Acid-d5 An internal standard for the quantification of 13-cis retinoic acid
- GC41907 13C C16 Sphingomyelin (d18:1/16:0) 13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion.
- GC41917 14-methyl Palmitic Acid 14-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, Aegean jellyfish (A.
- GC41166 15(S)-15-methyl Prostaglandin D2 15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2.
- GC41167 15(S)-15-methyl Prostaglandin E2 15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2.
- GC41924 15(S)-15-methyl Prostaglandin F2α isopropyl ester 15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor.
- GC18372 15(S)-15-methyl Prostaglandin F2α methyl ester 15(S)-15-methyl PGF2α methyl ester is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability.
- GC13960 15-deoxy-Δ-12,14-Prostaglandin J2 15-Desoxy-Δ-12,14-Prostaglandin J2 (15d-PGJ2) ist ein Cyclopentenon-Prostaglandin und ein Metabolit von PGD2.
- GC46447 15-deoxy-δ12,14-Prostaglandin J2-d4 An internal standard for the quantification of 15deoxyΔ12,14prostaglandin J2
- GC40582 15-keto Prostaglandin F1α 15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH.
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GC41418
15-keto Prostaglandin F2α
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α.
- GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.
-
GC41939
15-methyl Palmitic Acid
15-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, one-humped camel (C.
- GC18774 16,16-dimethyl Prostaglandin F2α 16,16-dimethyl PGF2α is a metabolically stable analog of PGF2α.
- GC49848 16-Ketoestradiol An active metabolite of estrone
- GC41946 16-phenoxy tetranor Prostaglandin F2α 16-phenoxy PGF2α is a metabolically stable analog of PGF2α.
- GC40961 16-phenoxy tetranor Prostaglandin F2α methyl ester Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
- GC41321 17α,20β-Dihydroxy-4-pregnen-3-one An endogenous, maturation-inducing steroid
- GC46470 17β-Estradiol-d2 1&7#946;-Estradiol-d2 (β-1&7#946;-Estradiol-d2) ist das mit Deuterium bezeichnete Estradiol.
- GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane.
- GC41955 17-DMAG 17-DMAG (17-DMAG) ist ein potenter Inhibitor von Hsp90, der an Hsp90 mit einem EC50 von 62 ± bindet; 29 nM.
- GC13044 17-DMAG (Alvespimycin) HCl 17-DMAG (Alvespimycin) HCl (17-DMAG Hydrochlorid; KOS-1022; BMS 826476) ist ein potenter Inhibitor von Hsp90, der an Hsp90 mit einem EC50 von 62±29 nM bindet.
- GC48819 17-Epiestriol A metabolite of estrone
- GC41966 17-phenyl trinor Prostaglandin E2 ethyl amide 17-phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively).
- GC40392 17-phenyl trinor Prostaglandin F2α methyl ester 17-Phenyltrinor Prostaglandin F2α Methylester ist ein Prodrug von Bimatoprost.
- GC41976 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC18816 19(R)-hydroxy Prostaglandin E1 19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man.
- GC49514 2′-Deoxyuridine-d2 An internal standard for the quantification of 2’-deoxyuridine
- GC52122 2’-Deoxyadenosine-5’-diphosphate (sodium salt) A nucleotide diphosphate
- GC46508 2',2'-Difluoro-2'-deoxyuridine An active metabolite of gemcitabine
- GC46540 2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate) A purine nucleotide
- GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) 2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.
- GC46509 2,3,4,5-Tetrachlorophenol A metabolite of γ-lindane
- GC42058 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose is a D-glucopyranose derivative that has been used in glucosylation reactions.
- GC13836 2,3-dihydrothieno-Thiadiazole Carboxylate CYP450 enzymes (CYP2E1 and CYP2B4) inhibitor
- GC48459 2,3-Indolobetulin A derivative of betulin
- GC48444 2,3-Indolobetulonic Acid An inhibitor of α-glucosidase
- GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols
- GC41470 2,5-Anhydro-D-mannitol 2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver..
- GC49159 2-(1-Piperazinyl)pyrimidine An α2-AR antagonist and active metabolite of azapirones
- GC49330 2-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyisoindol-1-one (hydrochloride) A metabolite of mazindol
- GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 2-(E-2-Decenoylamino)ethyl 2-(Cyclohexylethyl)sulfid ist eine Verbindung, die stressinduzierte GeschwÜre und geringe ToxizitÄt hemmt und den Gehalt an Phospholipase A2 und Prostaglandin E2 bei Ratten mit Ulzerationen, die durch unter Wasser eingetauchten zurÜckhaltenden Stress verursacht wurden, aufrechterhalten kann.
- GC65414 2-(Tetradecylthio)acetic acid 2-TetradecylthioessigsÄure ist ein Pan-Peroxisom-Proliferator-aktivierter Rezeptor (pan-PPAR)-Aktivator.
- GC13956 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide 2-Acetamidophenyl-5-chlor-2-nitrophenylsulfid (Verbindung 2) ist ein potenter PDE7 (Phosphodiesterase 7)-Inhibitor mit einem IC50-Wert von 2,1 μM.
- GC34186 2-Aminobenzenesulfonamide (Orthanilamide) 2-Aminobenzolsulfonamid (Orthanilamid) ist ein Carboanhydrase-IX-Hemmer.
- GC49609 2-bromo 17β-Estradiol A synthetic steroid and inhibitor of estrogen 2-hydroxylase
- GC49272 2-Chloro-4-nitrophenyl α-D-maltotrioside A colorimetric α-amylase substrate
- GC42137 2-Chloro-4-nitrophenyl-α-D-glucopyranoside Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate.
- GC46539 2-Chloroadenine A heterocyclic building block
-
GC41528
2-deoxy-2-fluoro L-Fucose
Fucose ist eine Deoxyhexose, die in vielen Organismen vorkommt.
- GC48943 2-deoxy-2-fluoro-D-Glucose A glucose derivative with anticancer activity
- GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.
- GC49223 2-deoxy-D-Glucose-13C6 An internal standard for the quantification of 2-deoxy-D-glucose
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GC19427
2-deoxy-D-Glucose-6-phosphate (sodium salt)
A synthetic analog of glucose used in cell metabolism and cancer research