ent-8-iso Prostaglandin F2α-d9 (Synonyms: ent-8-epi PGF2αd9, ent-8-iso PGF2αd9, ent-15-F2t-Isoprostane-d9)

Name: ent-8-iso Prostaglandin F2α-d9
Brand: GlpBio
SKU: GC47292
Availability: InStock
Rating: 5 (22 reviews)

Catalog No.GC47292

A neuropeptide with diverse biological activities

Products are for research use only. Not for human use. We do not sell to patients.

ent-8-iso Prostaglandin F2α-d9 Chemical Structure

Cas No.: N/A

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10 μg	$221.00	In stock
25 μg	$524.00	In stock
50 μg	$996.00	In stock
100 μg	$1,767.00	In stock

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Sample solution is provided at 25 µL, 10mM.

GlpBio Products Cited In Reputable Papers

Nature
610.7931 (2022): 366-372

Nature
618, 1017–1023 (2023)

Cell
183.7 (2020): 1867-1883

Cell Research
31, 1291–1307 (2021)

Cell Research
33, 273–287 (2023)

Cell Research
33, 546–561 (2023)

Molecular Cancer
21.1 (2022): 1-17

Molecular Cancer
21.1 (2022): 1-18

Cancer Cell
39 (2021): 1-16

Cell Host Microbe
30.8 (2022): 1124-1138

Cell Host Microbe
31.5 (2023): 766-780

Cell Host Microbe
31.3 (2023): 418-43

Cell Metabolism
34.2 (2022): 240-255

Ann Rheum Dis
82(4): 533-545 (2023)

Cell Mol Immunol
20, 264–276 (2023)

Adv Funct Mater
33.35 (2023): 2214998

Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

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Purity: >99.00%

ent-8-iso-Prostaglandin F_2α-d₉ (ent-8-iso-PGF_2α-d₉) contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19',20,20, and positions. It is intended for use as an internal standard for the quantification of ent-8-iso-PGF_2α by GC- or LC-mass spectrometry. Isoprostanes are produced by the non-enzymatic, free-radical peroxidation of arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have a potent biological activity. ent-8-iso Prostaglandin F_2α (ent-8-iso PGF_2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC₅₀ values of 31 and 54 nM, respectively.¹

1.Hou, X., Robers, L.J., II, Gobeil, F., Jr., et al.Isomer-specific contractile effects of a series of synthetic F2-isoprostanes on retinal and cerebral microvasculatureFree Radical Biology & Medicine36(2)163-172(2004)

Cas No.	N/A	SDF
Synonyms	ent-8-epi PGF2αd9, ent-8-iso PGF2αd9, ent-15-F2t-Isoprostane-d9
Canonical SMILES	O[C@H](C[C@H](O)[C@H]1/C=C/[C@H](O)CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])[C@@H]1C/C=C\CCCC(O)=O
Formula	C20H25D9O5	M.Wt	363.5
Solubility	DMF: >100 mg/ml,DMSO: >100 mg/ml,Ethanol: >100 mg/ml,PBS (pH 7.2): 3 mg/ml	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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		1 mg	5 mg	10 mg
	1 mM	2.751 mL	13.7552 mL	27.5103 mL
	5 mM	0.5502 mL	2.751 mL	5.5021 mL
	10 mM	0.2751 mL	1.3755 mL	2.751 mL

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for ent-8-iso Prostaglandin F2α-d9

Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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ent-8-iso Prostaglandin F2α-d9 (Synonyms: ent-8-epi PGF2αd9, ent-8-iso PGF2αd9, ent-15-F2t-Isoprostane-d9)

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