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Estragole (Synonyms: 4-Allylanisole, Methyl Chavicol, NSC 404113)

Catalog No.GC46141 Copy One-Click Copy Product Info

A volatile compound with diverse biological activities

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Estragole Chemical Structure

Cas No.: 140-67-0

Size Price Stock Qty
25g
$42.00
In stock
50g
$50.00
In stock
100g
$97.00
In stock

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Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Estragole

Estragole is a volatile compound that has been found in basil oil and has diverse biological activities.1,2,3,4 It induces mortality in 100% of adult C. capitata, B. dorsalis, and B. cucurbitae fruit flies exposed to wicks impregnated with estragole at concentrations greater than or equal to 2.5%.1 Estragole (60 mg/kg) reduces carrageenan-induced paw edema in mice.2 It increases survival in a mouse model of infection with the ME49 strain of T. gondii when administered at a dose of 100 mg/kg per day.3 Estragole (2.5 μmol/g, p.o., twice per week) increases the percentage of hepatoma-bearing mice and the average number of hepatomas per mouse in male, but not female, mice when administered prior to weaning.4

Chemical Properties of Estragole

Cas No. 140-67-0 SDF
Synonyms 4-Allylanisole, Methyl Chavicol, NSC 404113
Canonical SMILES COC1=CC=C(CC=C)C=C1
Formula C10H12O M.Wt 148.2
Solubility DMF: 10 mg/ml,Ethanol: Partially soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Estragole

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 6.7476 mL 33.7382 mL 67.4764 mL
5 mM 1.3495 mL 6.7476 mL 13.4953 mL
10 mM 674.8 μL 3.3738 mL 6.7476 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Estragole

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Reviews

Review for Estragole

Average Rating: 5 ★★★★★ (Based on Reviews and 24 reference(s) in Google Scholar.)

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