Ethylene Glycol monododecyl ether (Synonyms: C12E1, EGDE) |
| Catalog No.GC52061 |
A nonionic surfactant
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4536-30-5
Sample solution is provided at 25 µL, 10mM.
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Ethylene glycol monododecyl ether is a nonionic surfactant with a critical micelle concentration (CMC) of 27.5 µM at 25°C.1 It enhances the transdermal permeation of the antiemetic ondansetron across isolated porcine skin when used at a concentration of 160 mM, however, it decreases the viability of human epidermal keratinocytes and human dermal fibroblasts when used at a concentration of 160 µM.2
1.Islam, M.N., and Kato, T.Temperature dependence of the surface phase behavior and micelle formation of some nonionic surfactantsJ. Phys. Chem. B107(4)965-971(2003) 2.Silva, S.M.C., Hu, L., Sousa, J.J.S., et al.A combination of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondansetron HCl and diltiazem HClEur. J. Pharm. Biopharm.80(3)663-673(2012)
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