Ethylmalonyl Coenzyme A (sodium salt) (Synonyms: Ethylmalonyl-CoA) |
| Catalog No.GC47319 |
An intermediate in the ethylmalonyl CoA pathway in bacteria
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Sample solution is provided at 25 µL, 10mM.
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Ethylmalonyl coenzyme A (CoA) is a key intermediate in the ethylmalonyl-CoA pathway for carbon metabolism in certain bacteria, such as M. extorquens, which uses this pathway when grown on ethylamine.1,2 It is produced from crotonyl-CoA by crotonyl-CoA reductase/carboxylase and modified by ethylmalonyl-CoA mutase to make methylsuccinyl-CoA.
1.Good, N.M., Martinez-Gomez, N.C., Beck, D.A.C., et al.Ethylmalonyl coenzyme A mutase operates as a metabolic control point in Methylobacterium extorquens AM1J. Bacteriol.197(4)727-735(2015) 2.Anthony, C.How half a century of research was required to understand bacterial growth on C1 and C2 compounds; the story of the serine cycle and the ethylmalonyl-CoA pathwaySci. Prog.94(Pt 2)109-137(2011)
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