FFN 102 mesylate |
Catalog No.GC50120 |
Selective fluorescent substrate of DAT and VMAT2
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.
Rodriguez et al (2013) Fluorescent DA tracer resolves individual DArgic synapses and their activity in the brain. Proc.Natl.Acad.Sci.U.S.A. 110 870 PMID:23277566 |Sames et al (2013) Visualizing neurotransmitter secretion at individual synapses. ACS Chem.Neurosci. 4 648 PMID:23862751 |Lee et al (2010) Development of pH-responsive fluorescent false neurotransmitters. J.Am.Chem.Soc. 132 8828 PMID:20540519
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