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FFN 102 mesylate

Catalog No.GC50120

Selective fluorescent substrate of DAT and VMAT2

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FFN 102 mesylate Chemical Structure

Size Price Stock Qty
10 mg
$417.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.

Rodriguez et al (2013) Fluorescent DA tracer resolves individual DArgic synapses and their activity in the brain. Proc.Natl.Acad.Sci.U.S.A. 110 870 PMID:23277566 |Sames et al (2013) Visualizing neurotransmitter secretion at individual synapses. ACS Chem.Neurosci. 4 648 PMID:23862751 |Lee et al (2010) Development of pH-responsive fluorescent false neurotransmitters. J.Am.Chem.Soc. 132 8828 PMID:20540519

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