Home>>Fmoc-Cys(SASRIN™ resin)-OH (200-400 mesh, 0.3-0.6 mmol/g)

Fmoc-Cys(SASRIN™ resin)-OH (200-400 mesh, 0.3-0.6 mmol/g)

Catalog No.GA21562

This resin has been developed to allow C-terminal modification of cysteine-containing peptides. Fmoc-protected cysteine is linked to SASRIN™-resin by its thiol moiety, which thus is already protected. After derivatization of the carboxylic acid (and, if desired, standard Fmoc-SPPS) lthe modified cysteine derivative can be cleaved with TFA/water/triisopropylsilane (94:4:2, v/v/v) from the SASRIN™-resin. Extending the peptide chain at the C-terminus can be achieved by activation of the side-chain linked cysteine carboxylic acid and coupling to additional amino acids. Cys linked to a resin by its thiol function was oxidized with MCPBA after esterification and Nα-modification (Yamada et al.). DBU-induced elimination yielded dehydroalanine derivatives.

Products are for research use only. Not for human use. We do not sell to patients.

Fmoc-Cys(SASRIN™ resin)-OH (200-400 mesh, 0.3-0.6 mmol/g) Chemical Structure

Size Price Stock Qty
1g
$272.00
In stock
5g
$1,058.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

This resin has been developed to allow C-terminal modification of cysteine-containing peptides. Fmoc-protected cysteine is linked to SASRIN™-resin by its thiol moiety, which thus is already protected. After derivatization of the carboxylic acid (

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