H-His-Cys-Lys-Phe-Trp-Trp-OH |
| Catalog No.GA22534 |
HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3'processing and integration with an IC?? of 2 µM. The peptide is also active on IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus and Moloney murine leukemia virus. It was also found to inhibit the disintegration reaction, suggesting that this hexapeptide acts at or near the catalytic site of IN.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 172546-75-7
Sample solution is provided at 25 µL, 10mM.
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HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3'processing and integration with an IC50 of 2 µM. The peptide is also active on IN
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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