Bromoethyltriflate |
Catalog No.GD05616
One-Click Copy Product Info
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Bromoethyltriflate, a highly reactive chemical compound, serves as a potent alkylating agent.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 103935-47-3
Sample solution is provided at 25 µL, 10mM.
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Bromoethyltriflate, a highly reactive chemical compound, serves as a potent alkylating agent[1]. Bromoethyltriflate transfers ethyl groups to other molecules, which make it acts as a precursor in the synthesis of other alkylating agents and a valuable tool in synthesizing functionalized compounds[2]. Bromoethyltriflate is widely used in organic chemistry and pharmaceutical research area, particularly in the synthesis and modification of complex molecules or drug candidates[3][4].
References:
[1]. Matlock J V, Aggarwal V K, McGarrigle E M. (2‐Bromoethyl) diphenylsulfonium Trifluoromethanesulfonate[J]. Encyclopedia of Reagents for Organic Synthesis, 2001: 1-5.
[2]. Murali D, Barnhart TE, Vandehey NT, Christian BT, Nickles RJ, Converse AK, Larson JA, Holden JE, Schneider ML, Dejesus OT. An efficient synthesis of dopamine transporter tracer [¹⁸F]FECNT. Appl Radiat Isot. 2013 Feb;72:128-32. doi: 10.1016/j.apradiso.2012.10.010. Epub 2012 Oct 23. PMID: 23208243; PMCID: PMC3540169.
[3]. Zuhayra M, Alfteimi A, Papp L, Lützen U, Lützen A, Von Forstner C, Meller B, Henze E. Simplified fast and high yielding automated synthesis of [18F]fluoroethylcholine for prostate cancer imaging. Bioorg Med Chem. 2008 Oct 15;16(20):9121-6. doi: 10.1016/j.bmc.2008.09.031. Epub 2008 Sep 13. PMID: 18819809.
[4]. Liu, Zf., Wang, Gl., Dong, Mj. et al. Radiosynthesis of 10-(2-[18F]fluoroethoxy)-20(S)-camptothecin as a potential positron emission tomography tracer for the imaging of topoisomerase I in cancers. J Radioanal Nucl Chem 299, 1509–1515 (2014). https://doi.org/10.1007/s10967-013-2862-7
| Cas No. | 103935-47-3 | SDF | |
| Formula | C3H4BrF3O3S | M.Wt | 257.03 |
| Solubility | Storage | 2-8°C | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.8906 mL | 19.453 mL | 38.906 mL |
| 5 mM | 778.1 μL | 3.8906 mL | 7.7812 mL |
| 10 mM | 389.1 μL | 1.9453 mL | 3.8906 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.50% Appearance: A liquid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)