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2'-Fucosyllactose

Catalog No.GD13103 Copy One-Click Copy Product Info

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2'-Fucosyllactose Chemical Structure

Cas No.: 41263-94-9

Size Price Stock Qty
1mg
$31.00
In stock
5mg
$108.00
In stock
25mg
$374.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of 2'-Fucosyllactose

2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-纬 production and decreases IL-6, IL-17, and TNF-伪 production of cytokines.

2'-Fucosyllactose (2'-FL; 0-12 mg/mL; 48 h) suppress cell-associated CD14 expression and to attenuate LPS (100 渭g/mL) stimulated IL-8 secretion in T84 cells[1].
2'-Fucosyllactose (2 mg/mL; 48 h; T84 and HCT8 cells) ameliorates inflammation induced by bacterial invasion. 2'-Fucosyllactose inhibits ETEC invasion and attenuated the consequent IL-8 secretion[1].
2'-Fucosyllactose (2 mg/mL; 48 h; T84 and HCT8 cells) induces macrophage migration inhibitory factor signal pathways that suppress inflammation[1].

2'-Fucosyllactose (2'-FL; 100 mg (200 渭L); i.g.; daily, for 4 d; C57BL/6 mice with AIEC infection) inhibits AIEC infection and inflammation in vivo[1].

Chemical Properties of 2'-Fucosyllactose

Cas No. 41263-94-9 SDF
Formula C18H32O15 M.Wt 488.44
Solubility H2O : 50 mg/mL (102.37 mM; Need ultrasonic) Storage 2-8°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 2'-Fucosyllactose

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0473 mL 10.2367 mL 20.4733 mL
5 mM 409.5 μL 2.0473 mL 4.0947 mL
10 mM 204.7 μL 1.0237 mL 2.0473 mL
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In vivo Formulation Calculator (Clear solution) of 2'-Fucosyllactose

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for 2'-Fucosyllactose

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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