Perfluoropolyether carboxylic acid |
Catalog No.GF04814
One-Click Copy Product Info
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Perfluoropolyether carboxylic acid is a functional perfluoropolyether derivative. Perfluoropolyether carboxylic acid exhibits extremely low surface tension, high chemical stability, and high-temperature resistance; the terminal carboxyl group can react with metal ions, amines, etc., to form salt or ester derivatives.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 51798-33-5
Sample solution is provided at 25 µL, 10mM.
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Perfluoropolyether carboxylic acid is a functional perfluoropolyether derivative. Perfluoropolyether carboxylic acid exhibits extremely low surface tension, high chemical stability, and high-temperature resistance; the terminal carboxyl group can react with metal ions, amines, etc., to form salt or ester derivatives. Perfluoropolyether carboxylic acid can be used in high-performance lubricants, special coating materials, surfactants, and as a modifier for polymers and composites[1-4].
References:
[1] Wang J, Shi G, Yao J, et al. Perfluoropolyether carboxylic acids (novel alternatives to PFOA) impair zebrafish posterior swim bladder development via thyroid hormone disruption. Environ Int. 2020 Jan;134:105317..
[2] Guo H, Wang J, Yao J, et al. Comparative Hepatotoxicity of Novel PFOA Alternatives (Perfluoropolyether Carboxylic Acids) on Male Mice. Environ Sci Technol. 2019 Apr 2;53(7):3929-3937.
[3] Han H, Ding S, Geng Y,et al. Preparation of a pyridyl covalent organic framework via Heck cross-coupling for solid-phase microextraction of perfluoropolyether carboxylic acids in food. Food Chem. 2023 Mar 1;403:134310.
[4] Coperchini F, Greco A, Croce L, et al, Rotondi M. Do PFCAs drive the establishment of thyroid cancer microenvironment? Effects of C6O4, PFOA and PFHxA exposure in two models of human thyroid cells in primary culture. Environ Int. 2024 May;187:108717.
| Cas No. | 51798-33-5 | SDF | |
| Formula | F-(CF(CF3)CF2O)n-CF(CF3)COOH | M.Wt | 500-8000 |
| Solubility | Storage | Store at RT | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2 mL | 10 mL | 20 mL |
| 5 mM | 400 μL | 2 mL | 4 mL |
| 10 mM | 200 μL | 1 mL | 2 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Appearance: A liquid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)