Octakis(6-amino-6-deoxy)-γ-cyclodextrin |
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Catalog No.GF05119
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Octakis(6-amino-6-deoxy)-γ-cyclodextrin is a derivative of cyclodextrin and has enhanced water solubility.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 171283-79-7
Sample solution is provided at 25 µL, 10mM.
Octakis(6-amino-6-deoxy)-γ-cyclodextrin is a derivative of cyclodextrin and has enhanced water solubility[1]. Octakis(6-amino-6-deoxy)-γ-cyclodextrin can be used as a model compound to study the stability of the main body of modified cyclodextrin in aqueous solution[2]. Octakis(6-amino-6-deoxy)-γ-cyclodextrin can be used as a carrier host and coupled to a variety of molecules for different biomedical applications, especially for the loading of active drugs [3].
References:
[1] Florea M, Nau W M. Implementation of anion-receptor macrocycles in supramolecular tandem assays for enzymes involving nucleotides as substrates, products, and cofactors[J]. Organic & Biomolecular Chemistry, 2010, 8(5): 1033-1039.
[2] Van Guyse J F R, de la Rosa V R, Hoogenboom R. Mechanochemical preparation of stable sub‐100 nm γ‐cyclodextrin: Buckminsterfullerene (C60) nanoparticles by electrostatic or steric stabilization[J]. Chemistry–A European Journal, 2018, 24(11): 2758-2766.
[3] Odeh F, Adaileh F, Alshaer W, et al. Synthesis of mono-amino substituted γ-CD: host–guest complexation and in vitro cytotoxicity investigation[J]. Molecules, 2022, 27(5): 1683.
| Cas No. | 171283-79-7 | SDF | |
| Formula | M.Wt | ||
| Solubility | Storage | Store at RT | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)