4-Thiouridine-5'-Triphosphate

4-Thiouridine is useful for UV photocrosslinking studies to identify sites of ribonucleoprotein-RNA interactions and to crosslink sites containing RNA secondary and tertiary structure. Incorporation of 4-Thiouridine allows for specific crosslinking at longer wavelengths, typically between 320 and 360 nm, which results in minimal RNA damage compared to standard shortwave UV light. 4-Thiouridine-5'-Triphosphate can also be incorporated into RNA to allow specific and efficient tagging of the modified base with sulfur-reactive methylthiosulfonate-activated labels. "The 4-Thio-UTP I had ordered from GlpBio worked like a charm." Vaishnavi Rajagopal Post-doctoral Fellow Johns Hopkins University School of Medicine blank "We were impressed with the timing and the quality of the 4-Thio-UTP that we ordered. Obviously it is of utmost importance to our research that we are able to rely on companies such as GlpBio to provide quality products when we require them." Christine Woltjen Research Associate Ohio State University