GSK579289A |
| Catalog No.GC49280 |
A Plk1 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 929095-23-8
Sample solution is provided at 25 µL, 10mM.
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GSK579289A is an inhibitor of polo-like kinase 1 (Plk1; IC50 = 2 nM).1 It is selective for Plk1 over Plk3 (IC50 = 630 nM). GSK579289A inhibits proliferation of HCT116 cells (IC50 = 11 nM).
1.Rheault, T.R., Donaldson, K.H., Badiang-Alberti, J.G., et al.Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophenecarboxamides: Potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like propertiesBioorg. Med. Chem. Lett.20(15)4587-4592(2010)
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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