JWH 122 N-(5-hydroxypentyl) metabolite-d5 (Synonyms: MAM2201 N(5hydroxypentyl) metabolited5)

JWH 122 N-(5-hydroxypentyl) metabolite-d₅ contains five deuterium atoms at the 2, 4 ,5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 122 N-(5-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. JWH 122 is a synthetic cannabinoid (CB) of the naphthoylindole class that is structurally related to JWH 018 and JWH 073. It displays high-affinities for both CB₁ (K_i = 0.69 nM) and CB₂ (K_i = 1.2 nM) receptors.^1,2 JWH 122 N-(5-hydroxypentyl) metabolite is a metabolite of JWH 122 that is characterized by monohydroxylation of the N-alkyl chain. Currently, there are no reports of its biological activity.

1.Ernst, L., Schiebel, H.M., Theuring, C., et al.Identification and characterization of JWH-122 used as new ingredient in "spice-like" herbal incensesForensic Science International208(1-3)e31-35(2011) 2.Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y.Survey of current trends in the abuse of psychotropic substances and plants in JapanLeg. Med. (Tokyo)13(3)109-115(2011)