KBC-007 |
| Catalog No.GC43996 |
KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1037297-61-2
Sample solution is provided at 25 µL, 10mM.
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KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the survival rate of mice immunized with the inactivated influenza A virus A/PR/8/34 in a model of influenza infection.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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