- Cat.No. 상품명 정보
- GC62339 mTOR inhibitor-8 mTOR 억제제-8은 mTOR 억제제이자 자가포식 유도제입니다. mTOR 억제제-8은 FKBP12를 통해 mTOR의 활성을 억제하고 A549 인간 폐암 세포의 자가포식을 유도한다.
- GC31988 p38α inhibitor 1 p38&알파; 억제제 1은 특허 WO 2008076265 A1에서 추출한 p38α 억제제입니다.
- GC16531 Bromodomain Inhibitor, (+)-JQ1 A selective inhibitor of BET bromodomains
- GC65115 mTOR inhibitor-1 mTOR 억제제-1은 세포 증식을 억제하고 자가포식을 유도할 수 있는 새로운 mTOR 경로 억제제이다.
- GC36023 FAAH inhibitor 1 FAAH 억제제 1(벤조티아졸 유사체 3)은 IC50이 18±8 nM인 강력한 지방산 아미드 가수분해효소(FAAH) 억제제입니다.
- GC40694 Calpain Inhibitor II 칼페인 억제제 II(칼페인 억제제 II)는 칼페인 및 카텝신 프로테아제의 강력한 억제제입니다.
- GC10601 Ubiquitin Isopeptidase Inhibitor I Ubiquitin Isopeptidase Inhibitor I(NSC 144303)은 E1A 및 E1A/C9DN 세포에서 각각 1.76 및 1.6 μ의 IC50 값을 갖는 세포자멸사 독립 카스파제 및 세포자멸사 활성화제입니다.
- GC12527 Calpain Inhibitor I, ALLN A non-selective cysteine protease inhibitor
- GC35432 Autocamtide-2-related inhibitory peptide (TFA)
- GC65938 Thrombin inhibitor 5 트롬빈 억제제 5(화합물 385)는 0.1 μM 내지 1 μM 범위의 IC50을 갖는 트롬빈 억제제이다. 821d96072c2d58d8970e76f526b0f6b8트롬빈 억제제 5는 정맥 혈전색전증 연구에 사용할 수 있습니다.821d96072c2d58d8970e76f526b0f6b8
- GC17329 MLCK inhibitor peptide 18 MLCK 억제제 펩타이드 18은 IC50이 50nM인 미오신 경쇄 키나제(MLCK) 억제제이며 4000배 더 높은 농도에서만 CaM 키나제 II를 억제합니다.
- GC50305 Autocamtide-2-related inhibitory peptide, myristoylated Autocamtide-2 관련 억제 펩티드, myristoylated는 미리스토일화된 Autocamtide-2 관련 억제 펩티드입니다.
- GA23841 Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde Z-IE(OtBu)AL-CHO is an inhibitor of chymotrypsin-like activity of the multicatalytic proteinase complex (MPC; 20S proteasome) in HT4 cells. It is the first inhibitor reported so far which can cause accumulation of ubiquitinylated proteins in neuronal cells. Furthermore, this compound induced massive apoptosis in murine leukaemia L1210 cells. Therefore, proteasome inhibitors may be considered as potential anti-neoplastic agents.
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GC33715
Fluoxetine (LY-110140)
우울증 연구용 선택적 세로토닌 재흡수 억제제
- GC14396 Ponatinib (AP24534) 포나티닙(AP24534)(AP24534)은 Abl, PDGFR7777877888에 대해 IC50이 각각 0.37nM, 1.1nM, 1.5nM, 2.2nM, 2.2nM, 5.4nM인 경구 활성 다중 표적 키나제 억제제입니다.
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GC16973
DMOG
An HIF-PH inhibitor
- GC16499 Sorafenib Tosylate A multi-kinase inhibitor
- GC15344 SP 600125 A pan-JNK inhibitor
- GC13617 ZSTK474 A pan class I PI3K inhibitor
- GC13595 SB 203580 SB 203580 is a specific inhibitor of p38-MAPK (Mitogen-activated Protein Kinase) pathway .
- GC11118 KU 55933 An ATM kinase inhibitor
- GC11065 Pifithrin-μ Inhibitor of p53-mediated apoptosis
- GC10816 GDC-0941 A pan inhibitor of class I PI3K isoforms
- GC10060 BEZ235 (NVP-BEZ235) A dual inhibitor of class I PI3Ks and mTOR
- GC12660 AZD1208 A pan-Pim kinase inhibitor
- GC15571 SU 9516 A pro-apoptotic Cdk2/cyclin A inhibitor
- GC17783 Veliparib dihydrochloride An orally bioavailable inhibitor of PARP1 and PARP2
- GC16912 PD 150606 An inhibitor of calpains
- GC11640 MDL 28170 A cell permeable, selective calpain inhibitor
- GC10342 Calpeptin A calpain inhibitor
- GC15632 YM-155 hydrochloride A survivin inhibitor
- GC11007 VO-Ohpic trihydrate A specific inhibitor of PTEN
- GC14806 Vinorelbine ditartrate An inhibitor of microtubule polymerization
- GC12286 Vinblastine sulfate An inhibitor of microtubule assembly
- GC11876 Vandetanib hydrochloride A multi-kinase inhibitor
- GC13578 Skepinone-L An inhibitor of p38 MAPK
- GC17698 SJB2-043 An inhibitor of the USP1-UAF1 complex and SARS-CoV-2 PLpro
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GC11369
Sildenafil
A PDE5 inhibitor
- GC10054 SB 239063 A selective p38 MAPK inhibitor
- GC15785 Saquinavir mesylate An HIV protease inhibitor
- GC10528 Salirasib A Ras inhibitor with anti-cancer and anti-atherogenic activity
- GC18107 Salinomycin sodium salt A selective cancer stem cell inhibitor
- GC14882 Salinomycin A selective cancer stem cell inhibitor
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GC16124
Ruxolitinib phosphate
JAK1/JAK2의 강력하고 선택적인 억제제
- GC14534 Regorafenib monohydrate A multi-kinase inhibitor
- GC14606 Regorafenib hydrochloride A multi-kinase inhibitor
- GC16379 PI-103 Hydrochloride A potent, cell-permeable PI3K inhibitor
- GC10470 Nutlin-3a chiral An inhibitor of the p53-Mdm2 interaction
- GC18089 Nordihydroguaiaretic acid A non-selective LO inhibitor
- GC14237 Nilotinib monohydrochloride monohydrate A Bcr-Abl inhibitor
- GC17136 MRT67307 A kinase inhibitor
- GC15094 LY2183240 A potent, competitive inhibitor of anandamide uptake
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GC10629
KN-93
Ca2+/칼모딜린 의존성 키나제 II의 선택적 억제제
- GC15988 KN-92 hydrochloride An inactive control compound for a CaMKII inhibitor
- GC14132 KN-92 An inactive control compound for a CaMKII inhibitor
- GC15684 KB-R7943 mesylate An inhibitor of the reverse Na+/Ca2+ exchanger
- GC17534 GSK343 A selective, cell-permeable EZH2 inhibitor
- GC16154 GDC-0941 dimethanesulfonate A pan inhibitor of class I PI3K isoforms
- GC13535 Fluvastatin An HMG-CoA reductase inhibitor
- GC16063 Flavopiridol An inhibitor of cyclin-dependent kinases
- GC13022 Esomeprazole Magnesium trihydrate An H+/K+-ATPase inhibitor
- GC10627 Erlotinib An EGFR tyrosine kinase inhibitor
- GC16044 Emodin Natural CK2 inhibitor and ER agonist
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GC10466
EMD-1214063
EMD-1214063 (Tepotinib, MSC2156119J)은 새로운 강력하고 매우 선택적인 가역 ATP 경쟁 작은 분자 c-Met 억제제입니다.
- GC13202 D4476 Inhibitor of CK1 and ALK5
- GC16468 CYT387 sulfate salt A potent inhibitor of JAK1 and JAK2
- GC13065 Chelerythrine Chloride Potent inhibitor of PKC and Bcl-xL
- GC13365 CGI-1746 A potent, selective BTK inhibitor
- GC10707 Afatinib dimaleate An inhibitor of EGFR and ErbB2
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GC12511
Paclitaxel (Taxol)
A potent mitotic inhibitor
- GC16966 VER 155008 An Hsp70 inhibitor
- GC14308 FK866 (APO866) Inhibitor of nicotinamide phosphoribosyltransferase
- GC10330 Lonafarnib A farnesyltransferase inhibitor with antitumor activity
- GC16984 PF-3845 Inhibitor of FAAH
- GC15951 URB597 An inhibitor of FAAH
- GC14538 Pravastatin sodium A potent HMG-CoA reductase inhibitor
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GC14038
Atorvastatin Calcium
HMG-CoA 환원효소 억제제
- GC12801 Rasagiline Mesylate An inhibitor of MAO-B
- GC11633 Lovastatin An inhibitor of HMG-CoA reductase
- GC15541 Fluvastatin Sodium An HMG-CoA reductase inhibitor
- GC15890 Cilostazol A PDE3A inhibitor
- GC17685 Sildenafil Citrate A PDE5 inhibitor
- GC10486 Salinosporamide A (NPI-0052, Marizomib) An orally bioactive proteasome inhibitor
- GC15778 ONX-0914 (PR-957) A selective inhibitor of the β5i (LMP7) subunit of the immunoproteasome
- GC12793 RITA (NSC 652287) An inhibitor of the p53-HDM-2 interaction
- GC17162 MK-5108 (VX-689) A potent inhibitor of Aurora kinases
- GC17196 Hesperadin A multi-kinase inhibitor
- GC10638 AT9283 A broad spectrum kinase inhibitor
- GC15217 Danusertib (PHA-739358) A pan-Aurora kinase and Abl inhibitor
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GC14590
AR-42 (OSU-HDAC42)
HDAC inhibitor,novel and potent
- GC15114 LAQ824 (NVP-LAQ824,Dacinostat) A hydroxamate-based HDAC inhibitor
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GC10839
Tubastatin A
A potent HDAC6 inhibitor
- GC15794 Valproic acid sodium salt (Sodium valproate) A class I HDAC inhibitor
- GC14827 Linagliptin (BI-1356) A potent DPP-4 inhibitor
- GC11549 VX-680 (MK-0457,Tozasertib) An Aurora kinase inhibitor that regulates mitosis
- GC15315 Scriptaid HDAC inhibitor
- GC16497 SGI-1776 free base A potent inhibitor of Pim kinases
- GC15375 PFI-1 (PF-6405761) A BET bromodomain inhibitor
- GC14945 Sirtinol Inhibitor of sirtuin deacetylases
- GC13946 SNX-2112 A potent Hsp90 inhibitor