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Linoleic Acid glycidyl ester (Synonyms: C18:2-GE, C18:2 glycidyl ester, Glycidyl Linoleate, Glycidyl Octadecadienoate)

Catalog No.GC52113 Copy One-Click Copy Product Info

An esterified form of linoleic acid

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Linoleic Acid glycidyl ester Chemical Structure

Cas No.: 24305-63-3

Size Price Stock Qty
1 mg
$51.00
In stock
5 mg
$164.00
In stock
10 mg
$304.00
In stock
25 mg
$696.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of Linoleic Acid glycidyl ester

Linoleic acid glycidyl ester is an esterified form of linoleic acid containing a glycidyl group. It is hydrolyzed in vivo to glycidol, which is carcinogenic in rats.1 Linoleic acid glycidyl ester has been found in commercial edible oils and infant formulas.2,3

1.Cheng, W.-W., Liu, G.-Q., Wang, L.-Q., et al.Glycidyl fatty acid esters in refined edible oils: A review on formation, occurrence, analysis, and elimination methodsCompr. Rev. Food Sci. Food Saf.16(2)263-281(2017) 2.Masukawa, Y., Shiro, H., Nakamura, S., et al.A new analytical method for the quantification of glycidol fatty acid esters in edible oilsJ. Oleo Sci.59(2)81-88(2010) 3.Leigh, J., and MacMahon, S.Occurrence of 3-monochloropropanediol esters and glycidyl esters in commercial infant formulas in the United StatesFood Addit. Contam. Part A. Chem. Anal. Control Expo. Risk Assess.34(3)356-370(2017)

Chemical Properties of Linoleic Acid glycidyl ester

Cas No. 24305-63-3 SDF
Synonyms C18:2-GE, C18:2 glycidyl ester, Glycidyl Linoleate, Glycidyl Octadecadienoate
Canonical SMILES CCCCC/C=C\C/C=C\CCCCCCCC(OCC1CO1)=O
Formula C21H36O3 M.Wt 336.5
Solubility Chloroform: slightly soluble,Ethyl Acetate: slightly soluble,Methanol: slightly soluble,Methyl Acetate: soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Linoleic Acid glycidyl ester

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.9718 mL 14.8588 mL 29.7177 mL
5 mM 594.4 μL 2.9718 mL 5.9435 mL
10 mM 297.2 μL 1.4859 mL 2.9718 mL
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In vivo Formulation Calculator (Clear solution) of Linoleic Acid glycidyl ester

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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