MS049 oxalate salt |
| Catalog No.GC50236 |
Potent and selective PRMT4 and PRMT6 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Potent and selective PRMT4 and PRMT6 inhibitor (IC50 values are 44 and 63 nM, respectively). Reduces Med12me2a and H3R2me2a levels in HEK293 cells in vitro. To request the negative control for MS049, please fill out the MS049N request form on the SGC website.
Shen et al (2016) Discovery of a potent, selective, and cell-active dual inhibitor of protein arginine methyltransferase 4 and protein arginine methyltransferase 6. J.Med.Chem. 59 9124 PMID:27584694 |Scheer et al (2019) A chemical biology toolbox to study protein methyltransferases and epigenetic signaling. Nat.Commun. 10 19 PMID:30604761
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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