Oligonucleotides

Cat.No. Product Name Information

GC73120 AS 1411 sodium

AGRO-100 sodium

AS1411 sodium is a quadruplex-forming oligonucleotide aptamer that targets nucleolin. AS 1411 sodium Chemical Structure

GC64498 Cobomarsen

MRG-106

Cobomarsen (MRG-106) is an oligonucleotide inhibitor of miR-155. Cobomarsen inhibits multiple gene pathways associated with cell survival (including JAK/STAT, MAPK/ERK and PI3K/AKT). Cobomarsen can be used for the research of B-cell lymphoma. Cobomarsen Chemical Structure

GC64458 Golodirsen

SRP-4053

Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen Chemical Structure

GC64903 RGLS4326

RG4326

RGLS4326 (RG4326) is a first-in-class, short oligonucleotide inhibitor of microRNA-17 (miR-17). RGLS4326 Chemical Structure

GC64860 Rovanersen

WVE-120101

Rovanersen (WVE-120101) is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen Chemical Structure

GC81382 Sgc8c Aptamer Sgc8c Aptamer is a single-stranded DNA aptamer targeting protein tyrosine kinase 7 ( PTK7 ) with K d of 1.03-11.73 nM for human, mice, rat and monkey. Sgc8c Aptamer Chemical Structure

GC81381 Sgc8c-M

Sgc8c-VcMMAE

Sgc8c-M is a PTK7 -targeted aptamer-drug conjugate (ApDC). Sgc8c-M Chemical Structure

GC64871 Tominersen

RG6042; IONIS-HTTRx

Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen Chemical Structure

GC65493 Volanesorsen Volanesorsen is an antisense oligonucleotide thay targes Apolipoprotein C-III (APOC3) mRNA. Volanesorsen Chemical Structure

Oligonucleotides

Products for Oligonucleotides