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(R)-Aspartimide

Catalog No.GC46341

A byproduct in solid-phase peptide synthesis

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(R)-Aspartimide Chemical Structure

Cas No.: 404887-22-5

Size Price Stock Qty
1 mg
$111.00
In stock
5 mg
$335.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

(R)-Aspartimide is a byproduct formed during solid-phase peptide synthesis (SPPS) of aspartic acid-containing peptides.1 Aspartimide is formed by cyclization of aspartic acid during Fmoc removal or peptide coupling.2

1.Ruczyński, J., Lewandowska, B., Mucha, P., et al.Problem of aspartimide formation in Fmoc-based solid-phase peptide synthesis using Dmab group to protect side chain of aspartic acidJ. Pept. Sci.14(3)335-341(2008) 2.Neumann, K., Farnung, J., Baldauf, S., et al.Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groupsNat. Commun.11(1)982(2020)

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