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Home >> Signaling Pathways >> GPCR/G protein >> GPR119

GPR119

GPR119 is G-protein-coupled receptor for lipid amides OEA (oleoylethanolamide) and LPC (lysophosphatidylcholine). It may function in glucose homeostasis and insulin secretion. Act as a potential therapeutic target for type 2 diabetes.

Products for  GPR119

  1. Cat.No. Product Name Information
  2. GC40406 2-Oleoyl Glycerol

    2-Monoolein, 2-OG

    2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol.

     2-Oleoyl Glycerol Chemical Structure
  3. GC19033 APD597

    JNJ-38431055

     APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119. APD597 Chemical Structure
  4. GC12738 APD668

    JNJ-28630368

     Potent GPR119 agonist APD668 Chemical Structure
  5. GC14944 AR 231453 GPR119 agonist,potent and selective AR 231453 Chemical Structure
  6. GC12018 AS 1269574 GPR119 receptor agonist AS 1269574 Chemical Structure
  7. GC31508 Firuglipel

    DS-8500a

     Firuglipel (DS-8500a) is an orally available, potent and selective GPR119 agonist. Firuglipel Chemical Structure
  8. GC11434 GSK1292263 Novel GPR119 agonist GSK1292263 Chemical Structure
  9. GC12514 MBX-2982 An agonist of GPR119 MBX-2982 Chemical Structure
  10. GC13294 PSN 375963 hydrochloride PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 hydrochloride Chemical Structure
  11. GC10365 PSN632408 Human and mouse GPR119 agonist PSN632408 Chemical Structure

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