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Home >> Signaling Pathways >> GPCR/G protein >> GPR55

GPR55

GPR55 is a lysophosphatidylinositols and cannabinoids receptor. It is involved in various signaling cascade and plays a role in neuropathic/inflammatory pain, cancer and metabolic regulation etc.

Products for  GPR55

  1. Cat.No. Product Name Information
  2. GC12728 Abn-CBD

    AbnCBD, ortho-Cannabidiol, o-CBD

     GPR55 cannabinoid receptor agonist Abn-CBD Chemical Structure
  3. GC35339 Anandamide

    AEA, Anandamide

     An immune modulator in the central nervous system Anandamide Chemical Structure
  4. GC35694 CID 16020046 CID 16020046 is a potent and selective GPR55 antagonist and inhibits GPR55 constitutive activity with an IC50 of 0.15 μM. CID 16020046 inhibits GPR55-mediated Ca2+ signaling and GPR55-mediated ERK1/2 phosphorylation. CID 16020046 reduces wound healing in endothelial cells and is involved in the regulation of platelet function. CID 16020046 Chemical Structure
  5. GC73616 GPR55 agonist 4 GPR55 agonist 4 (Compound 28) is a GPR55 agonist (EC50: 131 nM, and 1.41 nM for hGPR55 and rGPR55). GPR55 agonist 4 Chemical Structure
  6. GC44217 ML-184

    CID-2440433

     GPR55 is a G protein-coupled receptor that is weakly activated by some cannabinoids (CBs) at nM concentrations but displays a 5- to 10-fold greater stimulation in response to 1 μM lysophosphatidylinositol (LPI). ML-184 Chemical Structure
  7. GC14026 ML-193

    CID-1261822

     GPR55 antagonist ML-193 Chemical Structure
  8. GC13513 O-1602

    Abn-CBDO, Abnormal Cannabidiorcin, Abnormal Cannabidiorcinol, Abnormal Cannabiorcodiol

    GPR55 cannabinoid receptor agonist

     O-1602 Chemical Structure
  9. GC16103 Oleylethanolamide

    Oleic Acid Ethanolamide, OEA

     Oleylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis. Oleylethanolamide Chemical Structure
  10. GC17777 Palmitoylethanolamide

    Palmidrol, PEA

     GPR55 agonist Palmitoylethanolamide Chemical Structure
  11. GC69771 PSB-SB-487

    PSB-SB-487 is an effective GPR55 antagonist and CB2 agonist, with an IC50 of 0.113 µM for GPR55 and a Ki of 0.292 µM for human CB2. PSB-SB-487 can be used to study diabetes, Parkinson's disease, neuropathic pain, and cancer.

     PSB-SB-487 Chemical Structure

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