EAAT2
Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter and functions to remove glutamate from synapses. An increase in EAAT2 protein expression and function may provide a means to prevent insufficient glutamate reuptake and consequently reduce neuronal damage.
The glial glutamate transporter EAAT2 plays a major role in glutamate clearance. EAAT2 can be upregulated by transcriptional or translational activation.EAAT2 is a potential target for the prevention of excitotoxicity.
Targets for EAAT2
Products for EAAT2
- Cat.No. Product Name Information
- GC38472 DL-TBOA An EAAT inhibitor
- GC64288 EAAT2 activator 1 EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2).
- GC31075 GT 949 A positive allosteric modulator of EEAT2
- GC10875 LDN 212320 increases expression of glutamate transporter EAAT2
- GC13659 WAY 213613 EAAT2 (GLT-1) inhibitor
- GC38524 WAY-213613 hydrochloride WAY-213613 (hydrochloride) is a potent and selective human EAAT2 inhibitor.