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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> NKCC

NKCC

NKCC (Na-K-Cl cotransporter) is an electrically silent membrane-bound channels that mediates Na and Cl reabsorption. It functions in regulating cell volume and ionic balance.

Products for  NKCC

  1. Cat.No. Product Name Information
  2. GC38738 Azosemide Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246??M and 0.197??M for hNKCC1A and NKCC1B, respectively. Azosemide Chemical Structure
  3. GC15524 Bumetanide

    PF-1593, Ro 10-6338

     NKCC cotransporter inhibitor Bumetanide Chemical Structure
  4. GC46957 Bumetanide-d5 An internal standard for the quantification of bumetanide Bumetanide-d5 Chemical Structure
  5. GC16795 DCA DCA is a metabolic regulator in cancer cells' mitochondria with anticancer activity. DCA inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. DCA increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. DCA also works as NKCC inhibitor. DCA Chemical Structure
  6. GC14041 Ethacrynic Acid

    MK 595,NSC 85791,NSC 624008

     Na+/K+/2Cl- cotransporter NKCC2 inhibitor Ethacrynic Acid Chemical Structure
  7. GC12970 Furosemide

    Frusemide, NSC 269420

     GABAA receptors antagonist Furosemide Chemical Structure
  8. GC36091 Furosemide sodium A loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter Furosemide sodium Chemical Structure

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