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Simazine-d10

Catalog No.GC49425 Copy One-Click Copy Product Info

An internal standard for the quantification of simazine

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Simazine-d10 Chemical Structure

Cas No.: 220621-39-6

Size Price Stock Qty
1 mg
$76.00
In stock
5 mg
$240.00
In stock
10 mg
$405.00
In stock
25 mg
$913.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of Simazine-d10

Simazine-d10 is intended for use as an internal standard for the quantification of simazine by GC- or LC-MS. Simazine is a triazine herbicide.1,2,3 Pre-emergent application of simazine (1 kg/ha) controls annual and perennial monocot and dicot weeds and increases crop yield in sorghum crops.1 It also controls weed emergence in kharif maize crops when applied at a concentration of 2 kg/ha.2 Simazine (200 and 400 mg/kg) induces spleen cell apoptosis and reduces the proliferation of B and T cells in mice.3 Formulations containing simazine have been used in the control of broadleaf weeds and annual grasses in agriculture.

1.Patro, G.K., Tosh, G.C., and Nayak, B.C.Weed control in sorghum through cultural and chemical methodsIndian J. Agric. Sci.42(12)1128-1131(1972) 2.Jadhav, S.N., and Khuspe, V.S.Relative efficacy of varying levels and times of application of simazine and atrazine on the control of weeds and yield of kharif maize (Zea mays Linn)J. Maharashtra Agric. Univ.6(2)169-171(1981) 3.Ren, R., Sun, D.-J., Yan, H., et al.Oral exposure to the herbicide simazine induces mouse spleen immunotoxicity and immune cell apoptosisToxicol. Pathol.41(1)63-72(2013)

Chemical Properties of Simazine-d10

Cas No. 220621-39-6 SDF
Canonical SMILES [2H]C([2H])([2H])C([2H])([2H])NC1=NC(Cl)=NC(NC([2H])([2H])C([2H])([2H])[2H])=N1
Formula C7H2ClD10N5 M.Wt 211.7
Solubility DMF: slightly soluble,DMSO: slightly soluble Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Simazine-d10

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.7237 mL 23.6183 mL 47.2367 mL
5 mM 944.7 μL 4.7237 mL 9.4473 mL
10 mM 472.4 μL 2.3618 mL 4.7237 mL
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In vivo Formulation Calculator (Clear solution) of Simazine-d10

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 2 reference(s) in Google Scholar.)

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