Simufilam dihydrochloride (Synonyms: PTI-125 dihydrochloride) |
| Catalog No.GC25935 |
Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
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Cas No.: 2480226-06-8
Sample solution is provided at 25 µL, 10mM.
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Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
[1] Hoau-Yan Wang, et al. Neurobiol Aging. 2017 Jul;55:99-114.
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