SRI-42127 |
Catalog No.GC69943 |
SRI-42127 is a HuR translocation inhibitor. HuR is an RNA regulatory factor that binds to ARE elements, and HuR translocation can promote the production of inflammatory cytokines in glial cells. SRI-42127 can disrupt mRNA stability and inhibit gene promoter activation. SRI-42127 also inhibits microglial activation, reducing the recruitment/chemotaxis of neutrophils and monocytes.
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Cas No.: 2727872-68-4
Sample solution is provided at 25 µL, 10mM.
Average Rating: 5
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