TCS 2314 |
| Catalog No.GC18025 |
integrin very late antigen-4 (VLA-4; α4β1) antagonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 317353-73-4
Sample solution is provided at 25 µL, 10mM.
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TCS 2314 (compound 3) is orally active and selective very late antigen-4 (VLA-4, α4β1, CD49d/CD29) antagonist with an IC50 of 4.4 nM[1].
References:
[1]. Muro F, et al. Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist. J Med Chem. 2009 Dec 24;52(24):7974-92.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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