YAP-TEAD Inhibitor 1 (Peptide 17) |
| Catalog No.GC26088 |
YAP-TEAD Inhibitor 1 (Peptide 17) is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1659305-78-8
Sample solution is provided at 25 µL, 10mM.
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YAP-TEAD Inhibitor 1 (Peptide 17) is a YAP-TEAD protein-protein interaction inhibitor which has potential usage in treatment of YAP-involved cancers with IC50 of 25 nM.
The engineered peptide significantly improves the potency in disrupting YAP-TEAD interaction in vitro[1]. This 17mer peptide demonstrates a single-digit micromolar affinity to TEAD1[2].
[1] Zhang Z, et al. ACS Med Chem Lett. 2014, 5(9):993-998. [2] Zhou Z, et al. FASEB J. 2015, 29(2):724-732.
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