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Hippo Signaling

Hippo signaling is a conserved pathway for organ size control by modulating cell proliferation, apoptosis and tissue-specific stem cell regeneration. It is associated with carcinogenesis.

Products for  Hippo Signaling

  1. Cat.No. Product Name Information
  2. GC32914 EMT inhibitor-1 EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. EMT inhibitor-1  Chemical Structure
  3. GC61410 I3MT-3 I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3  Chemical Structure
  4. GC14482 Verteporfin Verteporfin is a potent inhibitor of PD-L1 expression used for treatment in the age-related macular degeneration , port-wine stain birthmarks and cancer. Verteporfin  Chemical Structure
  5. GC11245 XMU-MP-1

    MST1/2 inhibitor, potent and selective

    XMU-MP-1  Chemical Structure

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