15(R)-Iloprost |
| Catalog No.GC40972 |
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 85026-51-3
Sample solution is provided at 25 µL, 10mM.
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Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP receptors with a Ki of 11 nM. 15(R)-Iloprost is the "unnatural" or inverted C-15 epimer of iloprost. This transformation frequently attenuates the biological agonist activity of prostaglandin analogs by several orders of magnitude. There are no literature reports of the biological activity of 15(R)-iloprost.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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