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(2S)-Octyl-α-hydroxyglutarate Catalog No.GC19473

A modified form of S-isomer 2-Hydroxyglutarate

Size Price Stock Qty
10 mM * 1 mL in DMSO
$206.00
In stock
1mg
$72.00
In stock
5mg
$216.00
In stock
10mg
$378.00
In stock
25mg
$846.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Chemical Properties

Cas No. 1391194-64-1 SDF Download SDF
Synonyms (2S)-Octyl-2-HG
Chemical Name N/A
Canonical SMILES O=C(OCCCCCCCC)[C@@H](O)CCC(O)=O
Formula C₁₃H₂₄O₅ M.Wt 260.33
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.

Treatment of IDH1-WT HeLa cells with (2S)-Octyl-α-hydroxyglutarate, a modified form of 2-Hydroxyglutarate with high cellular uptake, results in a dose-dependent increase in DSBs in log-phase cells[1].

Reference:

[1]. Sulkowski PL, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologousrecombination and induces PARP inhibitor sensitivity. Sci Transl Med. 2017 Feb 1;9(375).