5,6-Dihydrouridine (Synonyms: DHU) |
| Catalog No.GC33502 |
A pyrimidine nucleoside and derivative of uridine
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 5627-05-04
Sample solution is provided at 25 µL, 10mM.
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5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea.
5,6-Dihydrouridine (Dihydrouridine) is one of the posttranscriptionally modified nucleosides. It is a product of the reduction of uridine (U), and can be further modified to 5-methyldihydrouridine (m5D). 5,6-Dihydrouridine is commonly present in the tRNA from Bacteria, Eukaryota, and some Archaea. It is identified in six positions in the "D-loop" of the tRNA (16, 17, 20a, 20b) and in position 47 in the variable loop[1].
[1]. Kasprzak JM, et al. Molecular evolution of dihydrouridine synthases. BMC Bioinformatics. 2012 Jun 28;13:153.
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