Bacoside A3 (Synonyms: Bacopa Pgp) |
Catalog No.GC18312 |
Bacoside A3 is a triterpenoid saponin first isolated from B.
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Cas No.: 157408-08-7
Sample solution is provided at 25 µL, 10mM.
Bacoside A3 is a triterpenoid saponin first isolated from B. monniera. Bacoside A3 inhibits the ATP-binding cassette transporter P-glycoprotein (P-gp), decreasing efflux 4-fold compared with control in vitro. An extract containing bacoside A3 and bacopaside II (4 and 1.3 ug/mg extract, respectively) administered for eight days at a dose of 10-30 mg/kg reduces opioid withdrawal-induced depression in mice using the forced swim test. Bacoside A3 also has antioxidant properties following liver and kidney damage induced by street heroin in rats.
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