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β-Chloro-L-alanine (L-β-Chloroalanine) Catalog No.GC32328

Size Price Stock Qty
10mM*1mLinDMSO
$61.00
In stock
100mg
$56.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 2731-73-9 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES OC([C@@H](N)CCl)=O
Formula C3H6ClNO2 M.Wt 123.54
Solubility H2O : ≥ 30 mg/mL (242.84 mM) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.

β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B[1].

[1]. β-Chloro-L-alanine can inhibits threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli