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Bitoscanate (p-Phenylene diisothiocyanate)

Catalog No.GC32239 Copy One-Click Copy Product Info

Bitoscanate (p-Phenylene diisothiocyanate) (p-Phenylene diisothiocyanate) is an organic chemical compound used in the treatment of hookworms.

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Bitoscanate (p-Phenylene diisothiocyanate) Chemical Structure

Cas No.: 4044-65-9

Size Price Stock Qty
10mM (in 1mL DMSO)
$50.00
In stock
100mg
$46.00
In stock

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Bitoscanate (p-Phenylene diisothiocyanate)

Bitoscanate (p-Phenylene diisothiocyanate) is an organic chemical compound used in the treatment of hookworms.

[1]. Gaitonde BB, et al. Clinical evaluation of a new anthelmintic; phenylene di-iso thiocyanate (Bitoscanate) in hookworm and roundworm infestation. J Trop Med Hyg. 1969 Oct;72(10):253-8.

Chemical Properties of Bitoscanate (p-Phenylene diisothiocyanate)

Cas No. 4044-65-9 SDF
Canonical SMILES S=C=NC1=CC=C(N=C=S)C=C1
Formula C8H4N2S2 M.Wt 192.26
Solubility DMSO : 20 mg/mL (104.03 mM);Water : < 0.1 mg/mL (insoluble) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Bitoscanate (p-Phenylene diisothiocyanate)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.2013 mL 26.0064 mL 52.0129 mL
5 mM 1.0403 mL 5.2013 mL 10.4026 mL
10 mM 520.1 μL 2.6006 mL 5.2013 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Bitoscanate (p-Phenylene diisothiocyanate)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for Bitoscanate (p-Phenylene diisothiocyanate)

Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

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