Boc-MLF |
| Catalog No.GC11278 |
formyl peptide receptor 1 (FPR1) antagonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 67247-12-5
Sample solution is provided at 25 µL, 10mM.
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Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations[1].
Boc-MLF inhibits superoxide production induced by FPR agonist fMLF, with an EC50 of 630 nM in neutrophils[1].Boc-MLF (25 μM) blocks FPRL1-agonist serum amyloid A (SAA) induced calcium response[1].
References:
[1]. Stenfeldt AL, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30(6):224-9. Epub 2007 Aug 9.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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